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Novel Insights and Therapeutics in Multiple Sclerosis

F1000Research, ISSN: 1759-796X, Vol: 4, Issue: F1000 Faculty Rev, Page: 517
2015
  • 16
    Citations
  • 0
    Usage
  • 41
    Captures
  • 0
    Mentions
  • 10
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    16
  • Captures
    41
  • Social Media
    10
    • Shares, Likes & Comments
      10
      • Facebook
        10

Review Description

The last twelve years have witnessed the development of new therapies for relapsing-remitting multiple sclerosis that demonstrate increased efficacy relative to previous therapies. Many of these new drugs target the inflammatory phase of disease by manipulating different aspects of the immune system. While these new treatments are promising, the development of therapies for patients with progressive multiple sclerosis remains a significant challenge. We discuss the distinct mechanisms that may contribute to these two types of multiple sclerosis and the implications of these differences in the development of new therapeutic targets for this debilitating disease.

Bibliographic Details

Catriona A. Wagner; Joan M. Goverman

F1000 Research Ltd

Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Pharmacology, Toxicology and Pharmaceutics

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