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Alleviation of weight-gain in mice by an ethanolic extract from rubus coreanus under conditions of a high-fat diet and exercise

Bioscience, Biotechnology and Biochemistry, ISSN: 0916-8451, Vol: 77, Issue: 10, Page: 2148-2150
2013
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Article Description

The administration of an ethanolic extract (RCE) from Rubus coreanus significantly reduced the body weight and epididymal fat tissue of mice under conditions of a high-fat diet (HFD) and exercise. The mice also displayed enhanced muscular carnitine palmitoyltransferase 1 (CPT1) expression and increased superoxide dismutase and glutathione levels. These results suggest that RCE exerted an anti-obesity effect by upregulating CPT1 and elevating the level of antioxidants.

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