Senile plaques and phosphorylated tau deposition in a super-aged rhesus monkey (Macaca mulatta)
Journal of Veterinary Medical Science, ISSN: 1347-7439, Vol: 85, Issue: 12, Page: 1296-1300
2023
- 3Citations
- 2Captures
- 1Mentions
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
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- Citations3
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- Readers2
- Mentions1
- News Mentions1
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Senile plaques and phosphorylated tau deposition in a super-aged rhesus monkey (Macaca Mulatta).
J Vet Med Sci. 2023 Oct 12; Authors: Iwaide S, Nakayama Y, Chambers JK, Uchida K, Nakagawa D, Yamanashi Y, Bando H, Murakami T PubMed: 37821381 Submit Comment
Article Description
The brain of a rhesus monkey that died at 43 years of age with symptoms of suspected cognitive dysfunction was analyzed. pathological analyses revealed characteristic Alzheimer’s disease-related lesions: the aggregation of amyloid β (Aβ) in the form of senile plaques and phosphorylated tau proteins. We also revealed that Aβ43, which is prone to aggregation and toxicity in humans, is involved in senile plaques in the brain of the rhesus monkey, as well as several other Aβ species. Comparative studies of neuropathology using aged nonhuman primates lack behavioral descriptions compared to human medicine. This case report showed behavioral abnormalities and the detailed pathological changes that may have caused it in a super-aged rhesus monkey.
Bibliographic Details
Japanese Society of Veterinary Science
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