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Impact of particle softness on segregation of binary colloidal suspensions flowing in a microchannel

Kobunshi Ronbunshu, ISSN: 0386-2186, Vol: 76, Issue: 3, Page: 226-233
2019
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Article Description

In order to realize drug delivery systems, deeper understanding of the relationship between the position of colloidal particles, flowing in a microchannel, and particle characteristics, such as size and softness, is crucial. However, the influence of the softness of the particles on the flowing position (or segregation) in colloidal mixtures containing polymeric microspheres is still not clear. In this study, we investigated the particle position of binary mixtures in microchannels, observed by an optical microscope equipped with a high-speed camera, and clarified the effect of microgel softness on the segregation. These findings help designing carrier microspheres, for some applications, including drug delivery systems and as artificial blood cells.

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