Comparative analysis of various aspects of plateletpheresis on the Fenwal Amicus and Fresenius COM.TEC cell separator instruments
Laboratory Medicine, ISSN: 1943-7730, Vol: 45, Issue: 4, Page: 315-323
2014
- 3Citations
- 11Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations3
- Citation Indexes3
- CrossRef1
- Captures11
- Readers11
- 11
Article Description
Objective: To compare the Fenwal Amicus and the Fresenius COM.TEC apheresis instruments regarding donor peripheral blood parameters, operational variables of the instruments, and quality control parameters of the product obtained. Methods: We performed 100 platelet collections from 100 voluntary donors using the 2 studied devices. We measured platelet count using an automated analyzer and analyzed the activation statuses using a flow cytometer. Results: The median time needed to perform the procedures was significantly longer with the COM.TEC. However, the product we obtained using the Amicus instrument showed higher degrees of platelet-activation. All products we obtained with both instruments had white blood cell counts of less than 5 × 106 per bag. We observed no statistical difference regarding collection efficiency and collection rates between the devices. Conclusion: Both instruments collected platelets efficiently, with minimal donor discomfort. Compared with the COM.TEC instrument, the Amicus reached the platelet target yield more quickly; however, it displayed an increase in platelet activation.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84949685128&origin=inward; http://dx.doi.org/10.1309/lm491rnlmwlfhims; http://www.ncbi.nlm.nih.gov/pubmed/25316663; https://academic.oup.com/labmed/article-lookup/doi/10.1309/LM491RNLMWLFHIMS; http://academic.oup.com/labmed/article-pdf/45/4/315/8323243/labmed45-0315.pdf; http://dx.doi.org/10.1309/LM491RNLMWLFHIMS; https://dx.doi.org/10.1309/LM491RNLMWLFHIMS; https://academic.oup.com/labmed/article/45/4/315/2657824
Oxford University Press (OUP)
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