Significant correlation between refractive index and activity of mitochondria: Single mitochondrion study
Biomedical Optics Express, ISSN: 2156-7085, Vol: 6, Issue: 3, Page: 859-869
2015
- 45Citations
- 60Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations45
- Citation Indexes45
- CrossRef45
- 45
- Captures60
- Readers60
- 60
Article Description
Measurements of refractive indices (RIs) of intracellular components can provide useful information on the structure and function of cells. The present study reports, for the first time, determination of the RI of an isolated mitochondrion in isotonic solution using retardation-modulated differential interference contrast microscopy. The value was 1.41 ± 0.01, indicating that mitochondria are densely packed with molecules having high RIs. Further, the RIs of each mitochondrion were significantly correlated with the mitochondrial membrane potential, an index of mitochondrial activity. These results will provide useful information on the structures and functions of cells based on the intracellular distribution of RIs.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84942370256&origin=inward; http://dx.doi.org/10.1364/boe.6.000859; http://www.ncbi.nlm.nih.gov/pubmed/25798310; https://www.osapublishing.org/abstract.cfm?URI=boe-6-3-859; https://www.osapublishing.org/viewmedia.cfm?URI=boe-6-3-859&seq=0; https://opg.optica.org/abstract.cfm?URI=boe-6-3-859; https://dx.doi.org/10.1364/boe.6.000859; https://opg.optica.org/boe/fulltext.cfm?uri=boe-6-3-859&id=312122; https://opg.optica.org/abstract.cfm?uri=boe-6-3-859; https://opg.optica.org/viewmedia.cfm?uri=boe-6-3-859&seq=0&html=true; https://opg.optica.org/viewmedia.cfm?uri=boe-6-3-859&seq=0; https://opg.optica.org/boe/abstract.cfm?uri=boe-6-3-859; http://www.opticsinfobase.org/abstract.cfm?URI=boe-6-3-859; https://www.osapublishing.org/abstract.cfm?uri=boe-6-3-859; https://www.osapublishing.org/viewmedia.cfm?uri=boe-6-3-859&seq=0&html=true; https://www.osapublishing.org/viewmedia.cfm?uri=boe-6-3-859&seq=0; https://www.osapublishing.org/boe/abstract.cfm?uri=boe-6-3-859; https://www.osapublishing.org/boe/fulltext.cfm?uri=boe-6-3-859&id=312122
The Optical Society
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