Blind source unmixing in multi-spectral optoacoustic tomography
Optics Express, ISSN: 1094-4087, Vol: 19, Issue: 4, Page: 3175-3184
2011
- 111Citations
- 96Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations111
- Citation Indexes111
- 111
- CrossRef95
- Captures96
- Readers96
- 96
Article Description
Multispectral optoacoustic (photoacoustic) tomography (MSOT) is a hybrid modality that can image through several millimeters to centimeters of diffuse tissues, attaining resolutions typical of ultrasound imaging. The method can further identify tissue biomarkers by decomposing the spectral contributions of different photo-absorbing molecules of interest. In this work we investigate the performance of blind source unmixing methods and spectral fitting approaches in decomposing the contributions of fluorescent dyes from the tissue background, based on MSOT measurements in mice. We find blind unmixing as a promising method for accurate MSOT decomposition, suitable also for spectral unmixing in fluorescence imaging. We further demonstrate its capacity with temporal unmixing on real-time MSOT data obtained in-vivo for enhancing the visualization of absorber agent flow in the mouse vascular system. © 2011 Optical Society of America.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=79951657266&origin=inward; http://dx.doi.org/10.1364/oe.19.003175; http://www.ncbi.nlm.nih.gov/pubmed/21369139; https://www.osapublishing.org/oe/abstract.cfm?uri=oe-19-4-3175; https://www.osapublishing.org/viewmedia.cfm?URI=oe-19-4-3175&seq=0; https://opg.optica.org/oe/abstract.cfm?uri=oe-19-4-3175; https://dx.doi.org/10.1364/oe.19.003175
The Optical Society
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