The correlation between serum albumin and diabetic retinopathy among people with type 2 diabetes mellitus: NHANES 2011-2020
PLoS ONE, ISSN: 1932-6203, Vol: 17, Issue: 6 June, Page: e0270019
2022
- 14Citations
- 19Captures
- 5Mentions
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Metrics Details
- Citations14
- Citation Indexes14
- 14
- Captures19
- Readers19
- 19
- Mentions5
- News Mentions5
- News5
Most Recent News
Serum Globulin and Albumin-to-Globulin Ratio are Associated with Diabetic Kidney Disease but Not Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients: A Cross-Sectional Study
Ruo Zhang, Yang Jiao, Yuchao Wu, Lijing Yan, Chunhong Zhang, Jing Xu On behalf of the China National Diabetic Chronic Complications Study Group Department of
Article Description
Objectives The objective of this research aimed to investigate the correlation involving serum albumin with diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM). Methods From 2011 to 2020, the National Health and Nutrition Examination Survey (NHANES) surveyed 45462 participants. We used the relevant data to conduct descriptive statistics, linear regression, and Logistic regression analysis. Results After adjusting for age, sex, and race, as well as all other variables, serum albumin was significantly negatively related to DR (P<0.001). Furthermore, after controlling for confounding factors, the third quartile (Q3) and the fourth quartile (Q4) had quite a negative significant relationship with the incidence of DR (P<0.01). The second quartile had a significant positive correlation with DR, whereas the observed negative correlations were not statistically meaningful (P>0.05). Conclusion Albumin levels in the serum have a quantitatively significant negative correlation with DR. Serum albumin levels in the blood can be used as a reference point for protracted follow-up of people with T2DM.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85132079006&origin=inward; http://dx.doi.org/10.1371/journal.pone.0270019; http://www.ncbi.nlm.nih.gov/pubmed/35709212; https://dx.plos.org/10.1371/journal.pone.0270019; https://dx.doi.org/10.1371/journal.pone.0270019; https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0270019
Public Library of Science (PLoS)
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