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Cluster of Parechovirus Central Nervous System Infections in Young Infants — Tennessee, 2022

Morbidity and Mortality Weekly Report, ISSN: 1545-861X, Vol: 71, Issue: 30, Page: 977-978
2022
  • 16
    Citations
  • 0
    Usage
  • 10
    Captures
  • 79
    Mentions
  • 89
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    16
  • Captures
    10
  • Mentions
    79
    • News Mentions
      79
      • News
        79
  • Social Media
    89
    • Shares, Likes & Comments
      89
      • Facebook
        89

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Article Description

During April 12–May 24, 2022, 23 previously healthy infants aged 5 days–3 months were admitted to a Tennessee children’s hospital for human parechovirus (PeV) meningoencephalitis.* PeV is a nonenveloped RNA virus of the Picornaviridae family. PeV infections range from mild, self-limiting gastroenteritis to severe sepsis-like disease and central nervous system (CNS) infection, (1) and infants aged <3 months are disproportionately affected. PeV genotype 3 is responsible for the most severe cases, with a pattern of biannual cycle circulation that peaks during summer months (2,3). Although PeV infection is not a reportable disease, the Tennessee Department of Health was notified. An assessment of cases was conducted to better understand this unusually large cluster of infections

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