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Effect of proximal terminal colostomy on the healing of colonie anastomosis in rats

Acta Cirurgica Brasileira, ISSN: 1678-2674, Vol: 17, Issue: 6, Page: 398-402
2002
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Article Description

To evaluate the effects of the proximal-terminal colostomy on the healing of colonic anastomosis in rats. Methods:6 rats were allocated into two groups: control group (C) with 12 rats subjected to colonic ressectinon and primary anastomosis; colostomy group (CZ) with 24 rats subjected to the same procedure done in the group C, but complemented with a proximal-terminal colostomy. Anastomosis healing was evaluated at the 2 and 7 postoperative days (PO) by the presence of anastomotic dehiscence and mucosal line, adhesions, bursting pressure, and histologic examination. Results: There was no anastomotic dehiscence in the two groups. Adhesions were more intense in group C at the 7 PO. At both groups, the intestinal rupture was always on the anastomotic line at the 2 PO; at the 7 PO, most of ruptures happened on the colonic zone out of the anastomotic line (100% of group C and 70% of group CZ). No significant difference was noticied in the other healing anastomotic variables. Conclusion: There is no difference in the healing of colonic anastomosis related to the presence or abscence of a proximal colostomy in rats.

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