The quantitative and qualitative parameters of rhynthytocograms in methanol and formaldehyde impact in production environment

This study is devoted to assessing the state of the mucous membrane of the upper respiratory tract of the workers of chemical production of methanol and formaldehyde. A total of 450 workers were examined by rhinocytogram (RCH) evaluation. As a result of the study, studies have found that people with work experience of up to 10 years in the production of methanol and formaldehyde in the RCH the siggns of chronic inflammation is more likely to be detected. More experienced patients (more than 10 years of work experience) studies have found the establishment of morphological signs of protective and degenerative changes in ciliated epithelium, and there is a high degree of connection between the development of protective changes and the exposure to chemicals (RR = 2.71, etiological share, EF = 56.4%) and the development of degenerative changes (RR = 3.28, EF = 65.4%). These results are considered by the authors as the biomarkers of the development of a professionally conditioned lesion of the upper respiratory tract.