An assessment of endocrine disruption in Mollusks and the potential for developing internationally standardized mollusk life cycle test guidelines
Integrated Environmental Assessment and Management, ISSN: 1551-3793, Vol: 4, Issue: 3, Page: 274-284
2008
- 95Citations
- 98Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations95
- Citation Indexes93
- CrossRef93
- 90
- Policy Citations2
- Policy Citation2
- Captures98
- Readers98
- 98
Review Description
This paper summarizes what is known about the endocrine systems of mollusks and how they can be disrupted by exogenous substances. It then examines the various possibilities for using mollusk-based toxicity tests to detect and assess the environmental risks of endocrine-disrupting chemicals (EDCs). It is concluded that there are no internationally standardized tests with mollusks available at present that are suitable for assessing the risks of long-term exposure to EDCs but that several published methods show potential. At the present state of knowledge, the most promising mollusk species for use in partial life cycle testing is probably the fresh- and brackish-water mesogastropod, Potamopyrgus antipodarum, which is known to be responsive to both direct and indirect androgens and to estrogens (and their mimics). Less experience of full life cycle testing exists with mollusks, but the freshwater pulmonate gastropod Lymnaea stagnalis at present offers the best possibility for a practical procedure. In both cases, there is a need for substantial test optimization and validation before these procedures could form the basis of international guidelines. © 2008 SETAC.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=55249104778&origin=inward; http://dx.doi.org/10.1897/ieam_2008-003.1; http://www.ncbi.nlm.nih.gov/pubmed/18393578; http://doi.wiley.com/10.1897/IEAM_2008-003.1; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1897%2FIEAM_2008-003.1; https://academic.oup.com/ieam/article/4/3/274/7746536; https://dx.doi.org/10.1897/ieam_2008-003.1; https://setac.onlinelibrary.wiley.com/doi/abs/10.1897/IEAM_2008-003.1
Wiley-Blackwell
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