Necrotizing Fasciitis in a Patient on Long-Term Intramuscular Interferon-Beta for Multiple Sclerosis: A Case Report
JBJS Case Connector, ISSN: 2160-3251, Vol: 10, Issue: 1, Page: E0288-null
2020
- 3Citations
- 14Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations3
- Citation Indexes3
- CrossRef2
- Captures14
- Readers14
- 14
Article Description
Case:Immunomodulatory injections are becoming common long-term treatments for neuromuscular diseases such as multiple sclerosis (MS), although they carry a risk of local site infection. We describe a case of a 57-year-old man who developed necrotizing fasciitis of the anterior thigh secondary to intramuscular (IM) injections of interferon-beta-1A for MS, ultimately developing septic shock and requiring serial debridements for source control.Conclusions:This is the first reported case of necrotizing fasciitis from chronic IM injections for MS and deserves particular attention because of the immunosuppressive nature of the injections. In patients with underlying predisposing factors for infection, such as decubitus ulcers, it may be prudent to reconsider the administration route. Patients in hypermetabolic states should be closely monitored for impaired response to infections.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85082791885&origin=inward; http://dx.doi.org/10.2106/jbjs.cc.19.00288; http://www.ncbi.nlm.nih.gov/pubmed/32224665; https://journals.lww.com/10.2106/JBJS.CC.19.00288; https://dx.doi.org/10.2106/jbjs.cc.19.00288; https://journals.lww.com/jbjscc/Abstract/2020/03000/Necrotizing_Fasciitis_in_a_Patient_on_Long_Term.54.aspx
Ovid Technologies (Wolters Kluwer Health)
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