Alternation of gene expression levels in mesenchymal stem cells by applying positive dielectrophoresis
Analytical Sciences, ISSN: 1348-2246, Vol: 32, Issue: 11, Page: 1213-1216
2016
- 13Citations
- 10Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations13
- Citation Indexes13
- 13
- CrossRef11
- Captures10
- Readers10
- 10
Article Description
In this study, we investigated the effect of positive dielectrophoresis (DEP) on gene expression in mesenchymal stem cells. When applying an alternating current voltage, human bone marrow derived mesenchymal stem cells (UE7T-13) exhibited a positive DEP, and were compressed onto the electrode surface. The constructed device can easily control the DEP force to the cells by changing the frequency. Interestingly, gene expressions of the cell differentiation marker in UE7T-13 cells and the mechanical stimulation-susceptible one were changed by applying a positive DEP. These results suggested that the gene expression in mesenchymal stem cells can be regulated by applying mechanical stimulation derived from DEP.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84995877137&origin=inward; http://dx.doi.org/10.2116/analsci.32.1213; http://www.ncbi.nlm.nih.gov/pubmed/27829628; https://link.springer.com/10.2116/analsci.32.1213; https://dx.doi.org/10.2116/analsci.32.1213; https://link.springer.com/article/10.2116/analsci.32.1213; https://www.jstage.jst.go.jp/article/analsci/32/11/32_1213/_article/-char/en/; https://www.jstage.jst.go.jp/article/analsci/32/11/32_1213/_article/-char/ja/
Springer Science and Business Media LLC
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