Metabolomics of exhaled breath condensate by nuclear magnetic resonance spectroscopy and mass spectrometry: A methodological approach
Current Medicinal Chemistry, ISSN: 1875-533X, Vol: 27, Issue: 14, Page: 2381-2399
2020
- 12Citations
- 25Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations12
- Citation Indexes12
- 12
- CrossRef3
- Captures25
- Readers25
- 25
Review Description
Respiratory diseases present a very high prevalence in the general population, with an increase in morbidity, mortality and health-care expenses worldwide. They are complex and het-erogeneous pathologies that may present different pathological facets in different subjects, often with personal evolution. Therefore, there is a need to identify patients with similar characteristics, prognosis or treatment, defining the so-called phenotype, but also to mark specific differences within each phenotype, defining the endotypes. Biomarkers are very useful to study respiratory phenotypes and endotypes. Metabolomics, one of the recently introduced “omics”, is becoming a leading technique for biomarker discovery. For the airways, metabolomics appears to be well suited as the respiratory tract offers a natural matrix, the Exhaled Breath Condensate (EBC), in which several biomarkers can be measured. In this review, we will discuss the main methodological issues related to the application of Nuclear Magnetic Resonance (NMR) spectroscopy and Mass Spectrometry (MS) to EBC metabolomics for investi-gating respiratory diseases.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85056902914&origin=inward; http://dx.doi.org/10.2174/0929867325666181008122749; http://www.ncbi.nlm.nih.gov/pubmed/30295185; http://www.eurekaselect.com/166018/article; https://dx.doi.org/10.2174/0929867325666181008122749; https://www.eurekaselect.com/article/93493
Bentham Science Publishers Ltd.
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