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Kimura Disease as a Rare Cause of Eosinophil and Total IgE Elevation

Asthma Allergy Immunology, ISSN: 1308-9234, Vol: 22, Issue: 2, Page: 197-200
2024
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Article Description

Kimura disease (KD) is a rare, chronic, inf lammatory disorder of unknown etiology characterized by the development of subcutaneous lymphoid masses, usually in the head and neck region; regional lymphadenopathy; peripheral eosinophilia; and elevated levels of serum IgE. KD has been described in China and Japan as “eosinophilic hyperplastic lymphogranuloma” or “atypical granulation associated with hyperplastic abnormalities in the lymphoid tissue”. The precise prevalence and incidence and the pathogenesis of KD are unknown. Trauma, infection, an IgE-mediated hypersensitivity reaction, or autoimmune processes have been postulated as possible causes. In this article, we aimed to present a patient who was investigated with elevated serum total IgE and eosinophils and diagnosed as Kimura disease in the light of the current literature.

Bibliographic Details

Fatma Merve Tepetam; Seyma Ozden; Tugce Yakut; Selver Seda Mersin

Turkish National Society of Allergy and Clinical Immunology

Immunology and Microbiology; Medicine

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