Impact of Advanced Hybrid Closed Loop on Youth With High-Risk Type 1 Diabetes Using Multiple Daily Injections
Diabetes care, ISSN: 1935-5548, Vol: 46, Issue: 3, Page: 628-632
2023
- 25Citations
- 16Captures
- 10Mentions
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Metrics Details
- Citations25
- Citation Indexes23
- 23
- Policy Citations2
- Policy Citation2
- Captures16
- Readers16
- 16
- Mentions10
- News Mentions10
- News10
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Article Description
OBJECTIVE: To evaluate glycemic outcomes in youth (aged 13-25 years) with type 1 diabetes and high-risk glycemic control (HbA1c ≥8.5% [69 mmol/mol]) on multiple daily injection (MDI) therapy after transitioning to advanced hybrid closed loop (AHCL) therapy. RESEARCH DESIGN AND METHODS: This prospective, 3-month, single-arm, dual-center study enrolled 20 participants, and all completed the study. RESULTS: HbA1c decreased from 10.5 ± 2.1% (91.2 ± 22.8 mmol/mol) at baseline to 7.6 ± 1.1% (59.7 ± 11.9 mmol/mol), and time spent in target range 70-180 mg/dL (3.9-10.0 mmol/L) increased from 27.6 ± 13.2% at baseline to 66.5 ± 9.8% after 3 months of AHCL. Two episodes of diabetic ketoacidosis attributed to infusion set failure occurred. CONCLUSIONS: AHCL has the potential to improve suboptimal glycemia in youth with type 1 diabetes previously on MDI therapy.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85148679165&origin=inward; http://dx.doi.org/10.2337/dc22-1971; http://www.ncbi.nlm.nih.gov/pubmed/36689621; https://diabetesjournals.org/care/article/46/3/628/148297/Impact-of-Advanced-Hybrid-Closed-Loop-on-Youth; https://dx.doi.org/10.2337/dc22-1971
American Diabetes Association
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