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Step by step towards understanding gold glyconanoparticles as elements of the nanoworld

Chemical Papers, ISSN: 0366-6352, Vol: 61, Issue: 4, Page: 237-255
2007
  • 13
    Citations
  • 0
    Usage
  • 17
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    13
    • Citation Indexes
      13
  • Captures
    17

Review Description

Gold glyconanoparticles as elements of the nanoworld belong to a group of particles with diameters not exceeding 100 nm. This size scale makes them conformable to common biomolecules. A gold glyconanoparticle consists of three different parts: the gold core, the linkers, and saccharide ligands. The glycocalyx-like surface of these particles mimics the presentation of carbohydrate epitopes of cell surface glycoconjugates. As a consequence, gold glyconanoparticles provide inimitable tools for probing and manipulating the mechanisms of biological processes based on carbohydrate interactions. Each component of the gold glyconanoparticle has a profound effect on the nanoparticle's properties. Therefore, in this review, elucidation of the overall behavior and properties of gold glyconanoparticles is based on a step by step (component by component) description of the system. © Institute of Chemistry, Slovak Academy of Sciences 2007.

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