Development of a new sensitive ELISA for the determination of uteroglobin-related protein 1, a new potential biomarker
Biomarkers, ISSN: 1354-750X, Vol: 15, Issue: 7, Page: 619-624
2010
- 5Citations
- 6Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations5
- Citation Indexes5
- CrossRef2
- Captures6
- Readers6
Article Description
Uteroglobin-related protein 1 (UGRP-1) is a protein specifically secreted in airways, where it could play an anti-inflammatory role. We developed a sandwich enzyme-linked immunosorbent assay (ELISA) allowing the detection of UGRP-1 in serum, urine, and amniotic and pulmonary fluids. Concentrations of UGRP-1 determined by ELISA and latex immunoassay were correlated in sputum and bronchoalveolar lavage fluid (BALF). The pattern of UGRP-1 concentration resembled that of Clara cell protein, both proteins occurring in high concentrations in amniotic fluid, sputum and BALF and in much lower concentrations in serum and urine. These findings suggest that UGRP-1 might serve as a biomarker of respiratory epithelium integrity. © 2010 Informa UK, Ltd.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=77958573366&origin=inward; http://dx.doi.org/10.3109/1354750x.2010.508842; http://www.ncbi.nlm.nih.gov/pubmed/20843168; http://www.tandfonline.com/doi/full/10.3109/1354750X.2010.508842; http://www.tandfonline.com/doi/pdf/10.3109/1354750X.2010.508842
Informa UK Limited
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