Adjuvant Activity of Synthetic Cationic Amphiphiles for Production of IgG Antibody in Sprague Dawley Rats
Food Science and Technology Research, ISSN: 1344-6606, Vol: 7, Issue: 1, Page: 67-71
2001
- 4Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Captures4
- Readers4
Article Description
12GP2 and 14GP2, synthetic cationic amphiphiles, were examined in Sprague-Dawley rats for their adjuvant activity with ovalbumin (OVA) as antigen. Findings were compared with the activity of complete Freund's adjuvant (CFA) and aluminum hydroxide (Alum). Both amphiphiles induced OVA specific IgG comparable to the conventional adjuvants CFA or Alum, and total IgG levels of 12GP2 and 14GP2 groups were lower than the levels of other conventional adjuvants or with no adjuvant. Induction of OVA specific IgA and IgM were not observed. Examination of the effect of these adjuvants on T cell population of spleen lymphocytes showed that CD4/CD8 ratio, CD4 populations and CD8 populations in rats immunized with the four adjuvants differed. Therefore, these adjuvants have different mechanisms for exerting immunoadjuvant activities.
Bibliographic Details
Japanese Society for Food Science and Technology
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know