Stereotactic radiosurgery of brainstem cavernous malformations: A systematic review and meta-analysis: A review
Journal of Neurosurgery, ISSN: 1933-0693, Vol: 120, Issue: 4, Page: 982-987
2014
- 44Citations
- 62Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations44
- Citation Indexes41
- 41
- CrossRef27
- Policy Citations3
- Policy Citation3
- Captures62
- Readers62
- 62
Review Description
Object. Over the last two decades, stereotactic radiosurgery (SRS) has arisen as a promising approach in the management of brainstem cavernous malformations (CMs). In the present study, the authors report a systematic review and meta-analysis of the available published data regarding the radiosurgical management of brainstem CMs. Methods. To identify eligible studies, systematic searches for brainstem CMs treated with SRS were conducted in major scientific publication databases. The search yielded 5 studies, which were included in the meta-analysis. Data from 178 patients with brainstem CMs were extracted. Hemorrhage rates before and after SRS were calculated, a meta-analysis was performed, and the risk ratio (RR) was determined. Results. Four studies showed a statically significant reduction in the annual hemorrhage rate after SRS. The overall RR was 0.161 (95% CI 0.052-0.493; p = 0.001), and 21 patients (11.8%) had transient or permanent neurological deficits. Conclusions. The present meta-analysis for the radiosurgical management of brainstem CMs shows that SRS can decrease the rate of repeat hemorrhage and has a low rate of adverse effects compared with surgery. The authors suggest that SRS may be considered as an alternative treatment for brainstem CMs that are inoperable or have a high operative risk. ©AANS, 2014.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84897949383&origin=inward; http://dx.doi.org/10.3171/2013.12.jns13990; http://www.ncbi.nlm.nih.gov/pubmed/24506243; https://thejns.org/view/journals/j-neurosurg/120/4/article-p982.xml; http://thejns.org/doi/10.3171/2013.12.JNS13990; http://thejns.org/doi/pdf/10.3171/2013.12.JNS13990
Journal of Neurosurgery Publishing Group (JNSPG)
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