Polyclonal anti T-lymphocyte antibody therapy monitoring in kidney transplant recipients: comparison of CD3+ T cell and total lymphocyte counts
Einstein (Sao Paulo, Brazil), ISSN: 2317-6385, Vol: 16, Issue: 4, Page: eAO4278-null
2018
- 10Citations
- 1,145Usage
- 15Captures
Metric Options: Counts1 Year3 YearSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations10
- Citation Indexes10
- 10
- Usage1,145
- Full Text Views1,057
- 1,057
- Abstract Views88
- 88
- Captures15
- Readers15
- 15
Article Description
OBJECTIVE: To investigate the correlation between total lymphocyte and CD3+ T cell counts in peripheral blood in renal transplant patients treated with anti-thymocyte globulin, and discuss related outcomes. METHODS: A single-center, retrospective study involving 226 patients submitted to kidney transplant between 2008 and 2013, and treated with anti-thymocyte globulin for induction or treatment of cellular rejection. Doses were adjusted according to CD3+ T cell or total lymphocyte counts in peripheral blood. RESULTS: A total of 664 paired samples were analyzed. The Spearman's correlation coefficient was 0.416 (p<0.001) for all samples combined; the overall Kappa coefficient was 0.267 (p<0.001). Diagnostic parameters estimated based on total lymphocyte counts were also calculated using the number of CD3+ T cells (gold standard), with a cut off of >20 cells/mm3. CONCLUSION: Total lymphocyte and CD3+ T cell counts in peripheral blood are not equivalent monitoring strategies in anti-thymocyte globulin therapy.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85059796559&origin=inward; http://dx.doi.org/10.31744/einstein_journal/2018ao4278; http://www.ncbi.nlm.nih.gov/pubmed/30517367; https://journal.einstein.br/pt-br/article/monitoramento-da-terapia-com-anticorpo-policlonal-antilinfocitos-t-em-transplantados-renais-comparacao-da-contagem-de-celulas-t-cd3-e-de-linfocitos-totais/; http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082018000400213&lng=en&tlng=en; http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1679-45082018000400213&lng=en&tlng=en; http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082018000400213; http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1679-45082018000400213; https://dx.doi.org/10.31744/einstein_journal/2018ao4278
Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know