Risk factors for adverse outcome among patients with non-high risk pulmonary embolism
Ukrainian Journal of Cardiology, ISSN: 2664-4479, Vol: 31, Issue: 2, Page: 41-52
2024
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Article Description
The aim – to determine the factors which have influence on hospital mortality in patients with non-high risk pulmonary embolism (PE). Materials and methods. We analysed 635 medical cards of patients (pts) with diagnosis «Pulmonary Embolism (PE)» who were hospitalised to Kharkiv City Clinical Hospital No.8. during 01.01.2017 – 01.01.2023. The inclusion criteria was diagnosis «PE» verified by multispiral computed tomography angiography (CTPA) of pulmonary arteries and/or by autop-sy. Among the 635 pts, 530 were non-high risk. The non-high risk pts were divided into 2 groups: Group I – pts who were discharged with improved status (479 – 90.4 %), Group II – pts who died during hospitalisation (51 – 9.6 %). Clinical, anamnestic, biochemical, instrumental parameters, mortality rates were measured; statistical analysis was done. Results and discussion. The independent factors identified by multivariate vector analysis were associated with in-hos-pital mortality in pts with non-high risk PE: atrial fibrillation (AF), obesity, history of venous thromboembolism (VTE); lower levels of blood oxygen saturation (SpO), systolic blood pressure (SBP); higher mean pulmonary arterial pressure (PAP); heart rate (HR) ³ 110 beats/min. An ROC analysis was also performed to determine the thresholds of factors associated with in-hospital mortality in patients with non-high risk PE: SBP £ 124 mm Hg, HR ³ 110 bts/min, mean PAP ³ 54 mm Hg. Impact of AF on in-hospital mortality was depicted by Kaplan – Meier. Conclusions. Several factors were associated with increased in-hospital mortality in patients with non-high risk PE: age ˃ 54 years, SBP £ 124 mm Hg, history of VTE, obesity, AF; SpO £ 87 %, mean PAP ³ 54 mm Hg, HR ³ 110 bpm.
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