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Increasing macrolide and fluoroquinolone resistance in Mycoplasma genitalium

Emerging Infectious Diseases, ISSN: 1080-6059, Vol: 23, Issue: 5, Page: 809-812
2017
  • 137
    Citations
  • 0
    Usage
  • 95
    Captures
  • 155
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    137
  • Captures
    95
  • Mentions
    155
    • News Mentions
      151
      • News
        151
    • Blog Mentions
      4
      • Blog
        4

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Article Description

Escalating resistance to azithromycin and moxifloxacin is being reported for Mycoplasma genitalium in the Asia-Pacific region. Analyzing 140 infections, we found pretreatment fluoroquinolone-resistance mutations in parC (13.6%) and gyrA (5%). ParC S83 changes were associated with moxifloxacin failure. Macrolide/fluoroquinolone-resistance mutations were in 8.6% of specimens, for which recommended therapies would be ineffective.

Bibliographic Details

Murray, Gerald L; Bradshaw, Catriona S; Bissessor, Melanie; Danielewski, Jennifer; Garland, Suzanne M; Jensen, Jørgen S; Fairley, Christopher K; Tabrizi, Sepehr N

Centers for Disease Control and Prevention (CDC)

Medicine

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