Case report: A young man with non-rapid eye movement parasomnias in a KCNT1-related epilepsy family
Frontiers in Neurology, ISSN: 1664-2295, Vol: 14, Page: 1280348
2023
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Most Recent News
Data on Parasomnias Discussed by Researchers at Central South University (Case report: A young man with non-rapid eye movement parasomnias in a KCNT1-related epilepsy family)
2023 DEC 08 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Daily News -- Current study results on parasomnias
Article Description
Differentiating between non-rapid eye movement (NREM) parasomnias and sleep-related hypermotor epilepsy (SHE) is challenging, as they exhibit similar episodes during sleep. A relatively high prevalence of NREM parasomnias has been detected in families with SHE. However, the common pathophysiologic mechanism is not completely clear. There have been no previous reports of KCNT1-related SHE combined with NREM parasomnias. In this report, we describe a 17 years-old male patient from a KCNT1 mutation family who exhibited complex abnormal behaviors during sleep, which have been confirmed as epileptic seizures combined with NREM parasomnias through video-electroencephalogram (vEEG) and video-polysomnography (vPSG). The present article provides a reasoning process to evaluate unusual nocturnal behaviors. Furthermore, our analysis suggests a new potential association between NREM parasomnias and KCNT1 mutations.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85178958951&origin=inward; http://dx.doi.org/10.3389/fneur.2023.1280348; http://www.ncbi.nlm.nih.gov/pubmed/38073640; https://www.frontiersin.org/articles/10.3389/fneur.2023.1280348/full; https://dx.doi.org/10.3389/fneur.2023.1280348; https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1280348/full
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