The Shank3 interaction partner ProSAPiP1 regulates postsynaptic SPAR levels and the maturation of dendritic spines in hippocampal neurons
Frontiers in Synaptic Neuroscience, ISSN: 1663-3563, Vol: 8, Issue: MAY, Page: 13
2016
- 9Citations
- 26Captures
- 2Mentions
Metric Options: Counts1 Year3 YearSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations9
- Citation Indexes9
- CrossRef7
- Captures26
- Readers26
- 26
- Mentions2
- Blog Mentions1
- 1
- News Mentions1
- 1
Most Recent Blog
Medical News Today: Could this protein explain why drinking can be so pleasurable?
New research has identified a protein tied to structural changes that take place in one of the brain's reward centers after too much drinking.
Most Recent News
Medical News Today: Could this protein explain why drinking can be so pleasurable?
New research has identified a protein tied to structural changes that take place in one of the brain's reward centers after too much drinking.
Article Description
The postsynaptic density or PSD is a submembranous compartment containing a wide array of proteins that contribute to both morphology and function of excitatory glutamatergic synapses. In this study, we have analyzed functional aspects of the Fezzin ProSAP-interacting protein 1 (ProSAPiP1), an interaction partner of the well-known PSD proteins Shank3 and SPAR. Using lentiviral-mediated overexpression and knockdown of ProSAPiP1, we found that this protein is dispensable for the formation of both pre- and postsynaptic specializations per se. We further show that ProSAPiP1 regulates SPAR levels at the PSD and the maturation of dendritic spines. In line with previous findings on the ProSAPiP1 homolog PSD-Zip70, we conclude that Fezzins essentially contribute to the maturation of excitatory spine synapses.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84993949285&origin=inward; http://dx.doi.org/10.3389/fnsyn.2016.00013; http://www.ncbi.nlm.nih.gov/pubmed/27252646; http://journal.frontiersin.org/Article/10.3389/fnsyn.2016.00013/abstract; https://dx.doi.org/10.3389/fnsyn.2016.00013; https://www.frontiersin.org/journals/synaptic-neuroscience/articles/10.3389/fnsyn.2016.00013/full
Frontiers Media SA
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know