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The art of intraoperative glioma identification

Frontiers in Oncology, ISSN: 2234-943X, Vol: 5, Issue: JUL, Page: 175
2015
  • 35
    Citations
  • 0
    Usage
  • 87
    Captures
  • 0
    Mentions
  • 25
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    35
  • Captures
    87
  • Social Media
    25
    • Shares, Likes & Comments
      25
      • Facebook
        25

Article Description

A major dilemma in brain-tumor surgery is the identification of tumor boundaries to maximize tumor excision and minimize postoperative neurological damage. Gliomas, especially low-grade tumors, and normal brain have a similar color and texture, which poses a challenge to the neurosurgeon. Advances in glioma resection techniques combine the experience of the neurosurgeon and various advanced technologies. Intraoperative methods to delineate gliomas from normal tissue consist of (1) image-based navigation, (2) intraoperative sampling, (3) electrophysiological monitoring, and (4) enhanced visual tumor demarcation. The advantages and disadvantages of each technique are discussed. A combination of these methods is becoming widely accepted in routine glioma surgery. Gross total resection in conjunction with radiation, chemotherapy, or immune/gene therapy may increase the rates of cure in this devastating disease.

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