Molecular mechanisms and physiological functions of autophagy in kidney diseases
Frontiers in Pharmacology, ISSN: 1663-9812, Vol: 13, Page: 974829
2022
- 6Citations
- 8Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations6
- Citation Indexes6
- Captures8
- Readers8
Review Description
Autophagy is a highly conserved cellular progress for the degradation of cytoplasmic contents including micromolecules, misfolded proteins, and damaged organelles that has recently captured attention in kidney diseases. Basal autophagy plays a pivotal role in maintaining cell survival and kidney homeostasis. Accordingly, dysregulation of autophagy has implicated in the pathologies of kidney diseases. In this review, we summarize the multifaceted role of autophagy in kidney aging, maladaptive repair, tubulointerstitial fibrosis and discuss autophagy-related drugs in kidney diseases. However, uncertainty still remains as to the precise mechanisms of autophagy in kidney diseases. Further research is needed to clarify the accurate molecular mechanism of autophagy in kidney diseases, which will facilitate the discovery of a promising strategy for the prevention and treatment of kidney diseases.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85138010137&origin=inward; http://dx.doi.org/10.3389/fphar.2022.974829; http://www.ncbi.nlm.nih.gov/pubmed/36081940; https://www.frontiersin.org/articles/10.3389/fphar.2022.974829/full; https://dx.doi.org/10.3389/fphar.2022.974829; https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.974829/full
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