PlumX Metrics
Embed PlumX Metrics

Deep-learning based positron range correction of pet images

Applied Sciences (Switzerland), ISSN: 2076-3417, Vol: 11, Issue: 1, Page: 1-13
2021
  • 15
    Citations
  • 0
    Usage
  • 21
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    15
    • Citation Indexes
      14
    • Patent Family Citations
      1
      • 1
  • Captures
    21

Article Description

Positron emission tomography (PET) is a molecular imaging technique that provides a 3D image of functional processes in the body in vivo. Some of the radionuclides proposed for PET imaging emit high-energy positrons, which travel some distance before they annihilate (positron range), creating significant blurring in the reconstructed images. Their large positron range compromises the achievable spatial resolution of the system, which is more significant when using high-resolution scanners designed for the imaging of small animals. In this work, we trained a deep neural network named Deep-PRC to correct PET images for positron range effects. Deep-PRC was trained with modeled cases using a realistic Monte Carlo simulation tool that considers the positron energy distribution and the materials and tissues it propagates into. Quantification of the reconstructed PET images corrected with Deep-PRC showed that it was able to restore the images by up to 95% without any significant noise increase. The proposed method, which is accessible via Github, can provide an accurate positron range correction in a few seconds for a typical PET acquisition.

Bibliographic Details

Joaquín L. Herraiz; Adrián Bembibre; Alejandro López-Montes

MDPI AG

Materials Science; Physics and Astronomy; Engineering; Chemical Engineering; Computer Science

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know