Microwave-assisted synthesis and antifungal activity of some novel thioethers containing 1,2,4-triazole moiety
Applied Sciences (Switzerland), ISSN: 2076-3417, Vol: 5, Issue: 4, Page: 1211-1220
2015
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Article Description
A series of novel thioether derivatives containing 1,2,4-triazole moiety were designed and synthesized from 4-chlorophenol and ethyl 2-chloroacetate as starting materials by multi-step reactions under microwave irradiation, and their structures were characterized by H-NMR, MS and elemental analysis. The antifungal activity of title compounds was determined. The results indicated that some of title compounds exhibited moderate antifungal activity.
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