PlumX Metrics
Embed PlumX Metrics

Why Y RNAs? about versatile RNAs and their functions

Biomolecules, ISSN: 2218-273X, Vol: 3, Issue: 1, Page: 143-156
2013
  • 39
    Citations
  • 0
    Usage
  • 88
    Captures
  • 1
    Mentions
  • 1
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    39
  • Captures
    88
  • Mentions
    1
    • References
      1
      • Wikipedia
        1
  • Social Media
    1
    • Shares, Likes & Comments
      1
      • Facebook
        1

Review Description

Y RNAs constitute a family of highly conserved small noncoding RNAs (in humans: 83-112 nt; Y1, Y3, Y4 and Y5). They are transcribed from individual genes by RNA-polymerase III and fold into conserved stem-loop-structures. Although discovered 30 years ago, insights into the cellular and physiological role of Y RNAs remains incomplete. In this review, we will discuss knowledge on the structural properties, associated proteins and discuss proposed functions of Y RNAs. We suggest Y RNAs to be an integral part of ribonucleoprotein networks within cells and could therefore have substantial influence on many different cellular processes. Putative functions of Y RNAs include small RNA quality control, DNA replication, regulation of the cellular stress response and proliferation. This suggests Y RNAs as essential regulators of cell fate and indicates future avenues of research, which will provide novel insights into the role of small noncoding RNAs in gene expression. © 2013 by the authors; licensee MDPI, Basel, Switzerland.

Bibliographic Details

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know