PlumX Metrics
Embed PlumX Metrics

MRI-Guided Radiation Therapy for Prostate Cancer: The Next Frontier in Ultrahypofractionation

Cancers, ISSN: 2072-6694, Vol: 15, Issue: 18
2023
  • 4
    Citations
  • 0
    Usage
  • 21
    Captures
  • 2
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Most Recent News

New Prostate Cancer Study Findings Have Been Reported from David Geffen School of Medicine University of California Los Angeles (UCLA) (MRI-Guided Radiation Therapy for Prostate Cancer: The Next Frontier in Ultrahypofractionation)

2023 OCT 06 (NewsRx) -- By a News Reporter-Staff News Editor at Clinical Trials Daily -- New research on prostate cancer is the subject of

Review Description

Technological advances in MRI-guided radiation therapy (MRIgRT) have improved real-time visualization of the prostate and its surrounding structures over CT-guided radiation therapy. Seminal studies have demonstrated safe dose escalation achieved through ultrahypofractionation with MRIgRT due to planning target volume (PTV) margin reduction and treatment gating. On-table adaptation with MRI-based technologies can also incorporate real-time changes in target shape and volume and can reduce high doses of radiation to sensitive surrounding structures that may move into the treatment field. Ongoing clinical trials seek to refine ultrahypofractionated radiotherapy treatments for prostate cancer using MRIgRT. Though these studies have the potential to demonstrate improved biochemical control and reduced side effects, limitations concerning patient treatment times and operational workflows may preclude wide adoption of this technology outside of centers of excellence. In this review, we discuss the advantages and limitations of MRIgRT for prostate cancer, as well as clinical trials testing the efficacy and toxicity of ultrafractionation in patients with localized or post-prostatectomy recurrent prostate cancer.

Bibliographic Details

Benitez, Cecil M; Steinberg, Michael L; Cao, Minsong; Qi, X Sharon; Lamb, James M; Kishan, Amar U; Valle, Luca F

MDPI AG

Medicine; Biochemistry, Genetics and Molecular Biology

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know