Reduction of Blood Oxidative Stress Following Colorectal Cancer Resection
Cancers, ISSN: 2072-6694, Vol: 16, Issue: 20
2024
- 1Citations
- 8Captures
- 2Mentions
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Most Recent Blog
Cancers, Vol. 16, Pages 3550: Reduction of Blood Oxidative Stress Following Colorectal Cancer Resection
Cancers, Vol. 16, Pages 3550: Reduction of Blood Oxidative Stress Following Colorectal Cancer Resection Cancers doi: 10.3390/cancers16203550 Authors: Katsuji Sawai Takanori Goi Youhei Kimura Kenji
Most Recent News
Study Findings from University of Fukui Advance Knowledge in Colon Cancer (Reduction of Blood Oxidative Stress Following Colorectal Cancer Resection)
2024 NOV 05 (NewsRx) -- By a News Reporter-Staff News Editor at NewsRx Medical Devices Daily -- New research on colon cancer is the subject
Article Description
Colorectal cancer is a major global health burden, with surgical resection being the standard treatment aimed at curative tumor removal. Oxidative stress is crucial in colorectal cancer progression and prognosis. This study hypothesizes that the physical removal of colorectal cancer, a primary source of oxidative stress, would reduce blood levels of reactive oxygen metabolite derivatives (d-ROMs), a marker of oxidative stress. This study included 123 patients who underwent radical resection for colorectal cancer. d-ROM levels were measured before and after surgery. The clinicopathological analysis showed a correlation between preoperative d-ROM levels and tumor size. This study confirmed a significant reduction in d-ROM levels following tumor resection. The d-ROM ratio before and after tumor resection was significantly higher in cases with positive lymph node metastasis and larger tumor size. These results suggest that d-ROM levels could serve as a valuable biomarker for monitoring tumor burden in patients with colorectal cancer.
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