PlumX Metrics
Embed PlumX Metrics

Capecitabine-Induced Ileitis during Neoadjuvant Pelvic Radio-Chemotherapy for Locally Advanced Rectal Cancer: A Case Report with Literature Review

Current Oncology, ISSN: 1718-7729, Vol: 30, Issue: 10, Page: 9063-9077
2023
  • 2
    Citations
  • 0
    Usage
  • 14
    Captures
  • 1
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Most Recent News

University Hospital Researcher Discusses Findings in Rectal Cancer (Capecitabine-Induced Ileitis during Neoadjuvant Pelvic Radio-Chemotherapy for Locally Advanced Rectal Cancer: A Case Report with Literature Review)

2023 NOV 01 (NewsRx) -- By a News Reporter-Staff News Editor at NewsRx Drug Daily -- New study results on rectal cancer have been published.

Article Description

We report on a clinical case of capecitabine-induced acute ileitis in a patient treated with pre-operative concurrent chemoradiation with capecitabine for locally advanced rectal cancer and provide a comprehensive literature review. This a rare, but life-threatening, clinical situation, that clinicians should be aware of. Severe persistent diarrhea is the most frequent clinical feature and computed tomography is a valid tool for diagnosis. Conservative management includes capecitabine withdrawal, antidiarrheal therapy and endovenous hydration, together with dietary modifications and broad-spectrum antibiotics. Pelvic irradiation represents an adjunctive risk factor, which may increase the likelihood of occurrence of terminal ileitis. Early recognition and prompt intervention are crucial for successful clinical management.

Bibliographic Details

Brignoli, Andrea; Ferrara, Eleonora; Zannetti, Micol; Loi, Gianfranco; Forti, Laura; Socci, Carlo; Carriero, Alessandro; Gennari, Alessandra; Krengli, Marco; Franco, Pierfrancesco

MDPI AG

Medicine

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know