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Unraveling the wide spectrum of melanoma biomarkers

Diagnostics, ISSN: 2075-4418, Vol: 11, Issue: 8
2021
  • 61
    Citations
  • 0
    Usage
  • 37
    Captures
  • 1
    Mentions
  • 31
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    61
  • Captures
    37
  • Mentions
    1
    • Blog Mentions
      1
      • 1
  • Social Media
    31
    • Shares, Likes & Comments
      31
      • Facebook
        31

Most Recent Blog

Diagnostics, Vol. 11, Pages 1341: Unraveling the Wide Spectrum of Melanoma Biomarkers

Diagnostics, Vol. 11, Pages 1341: Unraveling the Wide Spectrum of Melanoma Biomarkers Diagnostics doi: 10.3390/diagnostics11081341 Authors: Antonios Revythis Sidrah Shah Mikolaj Kutka Michele Moschetta Mehmet

Review Description

The use of biomarkers in medicine has become essential in clinical practice in order to help with diagnosis, prognostication and prediction of treatment response. Since Alexander Breslow’s original report on “melanoma and prognostic values of thickness”, providing the first biomarker for melanoma, many promising new biomarkers have followed. These include serum markers, such as lactate dehydrogenase and S100 calcium-binding protein B. However, as our understanding of the DNA mutational profile progresses, new gene targets and proteins have been identified. These include point mutations, such as mutations of the BRAF gene and tumour suppressor gene tP53. At present, only a small number of the available biomarkers are being utilised, but this may soon change as more studies are published. The aim of this article is to provide a comprehensive review of melanoma biomarkers and their utility for current and, potentially, future clinical practice.

Bibliographic Details

Revythis, Antonios; Shah, Sidrah; Kutka, Mikolaj; Moschetta, Michele; Ozturk, Mehmet Akif; Pappas-Gogos, George; Ioannidou, Evangelia; Sheriff, Matin; Rassy, Elie; Boussios, Stergios

MDPI AG

Biochemistry, Genetics and Molecular Biology

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