New Insights in Pleural Mesothelioma Classification Update: Diagnostic Traps and Prognostic Implications
Diagnostics, ISSN: 2075-4418, Vol: 12, Issue: 12
2022
- 11Citations
- 14Captures
- 1Mentions
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations11
- Citation Indexes11
- 11
- CrossRef9
- Captures14
- Readers14
- 14
- Mentions1
- News Mentions1
- News1
Most Recent News
Study Findings on Mesotheliomas Reported by Researchers at Pisa University Hospital (New Insights in Pleural Mesothelioma Classification Update: Diagnostic Traps and Prognostic Implications)
2023 JAN 10 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Daily -- A new study on mesotheliomas is now available.
Review Description
The 2021 WHO Classification of Tumors of the Pleura has introduced significant changes in mesothelioma codification beyond the three current histological subtypes—epithelioid, sarcomatoid and biphasic. Major advances since the 2015 WHO classification include nuclear grading and the introduction of architectural patterns, cytological and stromal features for epithelioid diffuse mesothelioma. Mesothelioma in situ has been recognized as a diagnostic category. Demonstration of loss of BAP1 or MTAP by immunohistochemistry, or CDKN2A homozygous deletion by FISH, is valuable in establishing the diagnosis of epithelioid mesothelioma. Recent emerging data proved that grading and histological subtypes have prognostic implications and may be helpful to patient risk stratification and clinical management. Nevertheless, the latest mesothelioma classification increases the already non-negligible diagnostic pitfalls, especially concerning differential diagnosis of pre-invasive tumors. In this review, recent changes in histologic classification of mesothelioma and advances in molecular markers are presented and their relation to diagnostic challenges and prognostic implications is discussed.
Bibliographic Details
MDPI AG
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