Exergy analysis of the heart with a stenosis in the arterial valve
Entropy, ISSN: 1099-4300, Vol: 21, Issue: 6
2019
- 11Citations
- 16Captures
- 1Mentions
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations11
- Citation Indexes11
- 11
- CrossRef7
- Captures16
- Readers16
- 16
- Mentions1
- Blog Mentions1
- Blog1
Article Description
In the past decade, several articles have proposed the use of an exergy perspective to analyze physiological systems of the human body under different physical conditions. Such a perspective focuses on the exergy transformations and the efficiency of the biological processes. This may aid the medical field in assessments of a patient's physical health by means of an index (exergy efficiency) based on the quality of the energy conversion in a given process within the human heart. As a follow-up, a model was developed to describe the evolution of the transvalvular pressure gradient in the aortic valve as a function of stenosis severity. This model was created using physiological data from 40 patients available in the literature, as well as 32 operating points from different bileaflet aortic valve prosthesis. A linear regression results in values around 14.0 kPa for the pressure gradient in the most severe case, evolving from 1.0 kPa for a healthy scenario. The thermodynamic model assesses the irreversibilities associated with energy conversion processes related to metabolism: exergy destroyed at the valves, exergy increased in the flow, and the power of the heart. Results indicate that destroyed exergy reaches values of 10 W (almost 10% of total basal metabolic rate of the whole body). Exergy efficiency is 15% for a healthy heart, decreasing as a function of the severity of the stenosis to values lower than 5%.
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