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Exergy analysis of the heart with a stenosis in the arterial valve

Entropy, ISSN: 1099-4300, Vol: 21, Issue: 6
2019
  • 11
    Citations
  • 0
    Usage
  • 16
    Captures
  • 1
    Mentions
  • 1
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    11
  • Captures
    16
  • Mentions
    1
    • Blog Mentions
      1
      • Blog
        1
  • Social Media
    1
    • Shares, Likes & Comments
      1
      • Facebook
        1

Article Description

In the past decade, several articles have proposed the use of an exergy perspective to analyze physiological systems of the human body under different physical conditions. Such a perspective focuses on the exergy transformations and the efficiency of the biological processes. This may aid the medical field in assessments of a patient's physical health by means of an index (exergy efficiency) based on the quality of the energy conversion in a given process within the human heart. As a follow-up, a model was developed to describe the evolution of the transvalvular pressure gradient in the aortic valve as a function of stenosis severity. This model was created using physiological data from 40 patients available in the literature, as well as 32 operating points from different bileaflet aortic valve prosthesis. A linear regression results in values around 14.0 kPa for the pressure gradient in the most severe case, evolving from 1.0 kPa for a healthy scenario. The thermodynamic model assesses the irreversibilities associated with energy conversion processes related to metabolism: exergy destroyed at the valves, exergy increased in the flow, and the power of the heart. Results indicate that destroyed exergy reaches values of 10 W (almost 10% of total basal metabolic rate of the whole body). Exergy efficiency is 15% for a healthy heart, decreasing as a function of the severity of the stenosis to values lower than 5%.

Bibliographic Details

Brandão Roll, Julio; Leone Borges, Matheus; Keutenedjian Mady, Carlos Eduardo; de Oliveira Junior, Silvio

MDPI AG

Physics and Astronomy

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