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Treatment for Locally Resectable Stage IIIC1 Cervical Cancer: A Retrospective, Single-Institution Study

Healthcare (Switzerland), ISSN: 2227-9032, Vol: 11, Issue: 5
2023
  • 1
    Citations
  • 0
    Usage
  • 15
    Captures
  • 1
    Mentions
  • 26
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    1
  • Captures
    15
  • Mentions
    1
    • News Mentions
      1
      • News
        1
  • Social Media
    26
    • Shares, Likes & Comments
      26
      • Facebook
        26

Most Recent News

Research from Kindai University Provides New Data on Cervical Cancer (Treatment for Locally Resectable Stage IIIC1 Cervical Cancer: A Retrospective, Single-Institution Study)

2023 MAR 15 (NewsRx) -- By a News Reporter-Staff News Editor at NewsRx Women's Health Daily -- Data detailed on cervical cancer have been presented.

Article Description

According to the revision of the FIGO 2018 staging system, cervical cancer with pelvic lymph node metastases was changed to stage IIIC1. We retrospectively analyzed the prognosis and complications of locally resectable (classified as T1/T2 by TNM classification of the Union for International Cancer Control) stage IIIC1 cervical cancer. A total of 43 patients were divided into three groups: surgery with chemotherapy (CT) (ope+CT group) (T1; n = 7, T2; n = 16), surgery followed by concurrent chemoradiotherapy (CCRT), or radiotherapy (RT) (ope+RT group) (T1; n = 5, T2; n = 9), and CCRT or RT alone (RT group) (T1; n = 0, T2; n = 6). In T1 patients, recurrence was observed in three patients, but there was no difference among the treatment groups, and no patients died. In contrast, in T2 patients, recurrence and death were observed in nine patients (8 in ope+CT; 1 in ope+RT), and recurrence-free survival and overall survival were lower in the ope+CT group (p = 0.02 and 0.04, respectively). Lymphedema and dysuria were more common in the ope+RT group. A randomized controlled trial comparing CT and CCRT as an adjuvant therapy after surgery in T1/T2 patients, including those with pelvic lymph node metastases, is currently underway. However, our data suggest that performing CT alone after surgery in T2N1 patients is likely to worsen the prognosis.

Bibliographic Details

Kashima, Yoko; Murakami, Kosuke; Miyagawa, Chiho; Takaya, Hisamitsu; Kotani, Yasushi; Nakai, Hidekatsu; Matsumura, Noriomi

MDPI AG

Nursing; Medicine; Health Professions

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