Liposomes with an ethanol fraction as an application for drug delivery
International Journal of Molecular Sciences, ISSN: 1422-0067, Vol: 19, Issue: 12
2018
- 46Citations
- 75Captures
- 2Mentions
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations46
- Citation Indexes46
- 46
- CrossRef35
- Captures75
- Readers75
- 75
- Mentions2
- Blog Mentions1
- Blog1
- News Mentions1
- News1
Most Recent News
Factorial Design for the Optimization of Clindamycin HCl-Loaded Ethosome with various concentrations of Phospholipon 90g and Ethanol
Elsa Fitria Apriani1*, Shaum Shiyan1, Dwi Hardestyariki2, Viva Starlista1, Mariska Febriani1 1Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Sriwijaya University, South Sumatra, Indonesia.
Review Description
Liposomes containing a certain amount of ethanol are often referred to in the literature as ethosomes. Liposomes vary in size from 25 nm to 25,000 nm. Ethosomes are defined as lipids composed of phospholipids, ethanol, or isopropyl alcohol in quite high concentrations, and water. They enable active substances to reach the deep skin layers or even the general circulation. The structure of ethosomes allows for an increased penetration of the drug through two effects: the ethanolic effect and the ethosomal effect. Ethosomes can be obtained using three methods: the hot method, the cold method, and the classic method of mechanical dispersion. The literature describes many of the therapeutic groups of drugs that can be enclosed in ethosomal formulations. These include anti-viral drugs, antineoplastic drugs, antifungal drugs, hypnotic drugs, hormones, and many others. Ethosomes show important practical advantages compared to classic liposomes. It is necessary to conduct research with regard to real pharmaceutical systems using advanced physicochemical techniques.
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