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Transmission electron microscopy as a powerful tool to investigate the interaction of nanoparticles with subcellular structures

International Journal of Molecular Sciences, ISSN: 1422-0067, Vol: 22, Issue: 23
2021
  • 100
    Citations
  • 0
    Usage
  • 358
    Captures
  • 2
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    100
  • Captures
    358
  • Mentions
    2
    • News Mentions
      2
      • News
        2

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Review Description

Nanomedical research necessarily involves the study of the interactions between nano-particulates and the biological environment. Transmission electron microscopy has proven to be a powerful tool in providing information about nanoparticle uptake, biodistribution and relation-ships with cell and tissue components, thanks to its high resolution. This article aims to overview the transmission electron microscopy techniques used to explore the impact of nanoconstructs on biological systems, highlighting the functional value of ultrastructural morphology, histochemistry and microanalysis as well as their fundamental contribution to the advancement of nanomedicine.

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