A Comparative Study of Acute Gastroenteritis Symptoms in Single- versus Multiple-Virus Infections
International Journal of Molecular Sciences, ISSN: 1422-0067, Vol: 24, Issue: 9
2023
- 5Citations
- 13Captures
- 1Mentions
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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- Citations5
- Citation Indexes5
- Captures13
- Readers13
- 13
- Mentions1
- Blog Mentions1
- 1
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IJMS, Vol. 24, Pages 8364: A Comparative Study of Acute Gastroenteritis Symptoms in Single- versus Multiple-Virus Infections
IJMS, Vol. 24, Pages 8364: A Comparative Study of Acute Gastroenteritis Symptoms in Single- versus Multiple-Virus Infections International Journal of Molecular Sciences doi: 10.3390/ijms24098364 Authors:
Article Description
Many different enteric viruses can cause acute gastroenteritis in humans worldwide. While a single virus can indeed cause disease, multiple-virus infections are commonly reported. However, data regarding a comparison between single- and multiple-virus infections upon clinical manifestations of acute gastroenteritis are relatively limited. In this study, a total of 2383 fecal specimens were collected from children with acute gastroenteritis during June 2014–July 2017 in a pediatric clinic in Japan and tested for 11 viruses by multiplex RT-PCR. At least 1 virus was found in 1706 (71.6%) specimens and norovirus GII was the most frequent agent, followed by rotavirus A and other viruses. Multiple-virus infections were identified in 565 cases (33.1%). While major clinical symptoms were found to be significantly different in some single- vs. multiple-virus infections, the disease severity was statistically non-significant. Our study highlights the burden of multiple-virus infections for acute gastroenteritis and the clinical features of patients with multiple-virus infections.
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