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β,β-Difluoro Peroxides as Fluorinated C2-Building Blocks for the Construction of Functionalized Indolizines

Molecules, ISSN: 1420-3049, Vol: 29, Issue: 24
2024
  • 0
    Citations
  • 0
    Usage
  • 1
    Captures
  • 1
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Captures
    1
  • Mentions
    1
    • Blog Mentions
      1
      • Blog
        1

Article Description

An effective method for the construction of functionalized indolizines has been developed in which β,β-difluoro peroxides act as novel C2-building blocks to implement [3+2] annulation with pyridinium ylides under base-mediated conditions. With this protocol, a broad range of multisubstituted indolizines were prepared in moderate to good yields under mild conditions, and many useful functional groups were tolerated.

Bibliographic Details

Yangyang Ma; Xiaoxiao Du; Shurui Fang; Kexin Yin; Gangfeng Du; Zhengshan Tian; Hua Zhang; Zhonghao Zhou

MDPI AG

Chemistry; Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics

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