Non-Toxin-Based Clostridioides difficile Vaccination Approaches
Pathogens, ISSN: 2076-0817, Vol: 12, Issue: 2
2023
- 16Citations
- 10Captures
- 2Mentions
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations16
- Citation Indexes12
- 12
- CrossRef3
- Policy Citations3
- 3
- Patent Family Citations1
- 1
- Captures10
- Readers10
- 10
- Mentions2
- Blog Mentions1
- 1
- News Mentions1
- 1
Most Recent Blog
Pathogens, Vol. 12, Pages 235: Non-Toxin-Based Clostridioides difficile Vaccination Approaches
Pathogens, Vol. 12, Pages 235: Non-Toxin-Based Clostridioides difficile Vaccination Approaches Pathogens doi: 10.3390/pathogens12020235 Authors: Agnieszka Razim Sabina Górska Andrzej Gamian Clostridioides difficile (CD) is a
Most Recent News
Managing Recurrent C difficile Infections: Past, Present, and Future; Pharmacy Practice in Focus: Health SystemsJanuary 2024 Volume 13 Issue 1 Article
Clostridioides difficile is a gram-positive, spore-forming bacterium found naturally in the environment.1 Human gastrointestinal tracts often carry C difficile asymptomatically, and a healthy microbiota defends
Review Description
Clostridioides difficile (CD) is a Gram-positive, anaerobic bacterium that infects mainly hospitalized and elderly people who have been treated with long-term antibiotic therapy leading to dysbiosis. The deteriorating demographic structure and the increase in the number of antibiotics used indicate that the problem of CD infections (CDI) will continue to increase. Thus far, there is no vaccine against CD on the market. Unfortunately, clinical trials conducted using the CD toxin-based antigens did not show sufficiently high efficacy, because they did not prevent colonization and transmission between patients. It seems that the vaccine should also include antigens found in the bacterium itself or its spores in order not only to fight the effects of toxins but also to prevent the colonization of the patient. This literature review summarizes the latest advances in research into vaccine antigens that do not contain CD toxins.
Bibliographic Details
MDPI AG
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