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The dynamics of HCF-1 modulation of herpes simplex virus chromatin during initiation of infection

Viruses, ISSN: 1999-4915, Vol: 5, Issue: 5, Page: 1272-1291
2013
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Article Description

Successful infection of herpes simplex virus is dependent upon chromatin modulation by the cellular coactivator host cell factor-1 (HCF-1). This review focuses on the multiple chromatin modulation components associated with HCF-1 and the chromatinrelated dynamics mediated by this coactivator that lead to the initiation of herpes simplex virus (HSV) immediate early gene expression. © 2013 by the authors; licensee MDPI, Basel, Switzerland.

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