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Cowpox virus: What’s in a name?

Viruses, ISSN: 1999-4915, Vol: 9, Issue: 5
2017
  • 40
    Citations
  • 0
    Usage
  • 36
    Captures
  • 2
    Mentions
  • 0
    Social Media
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Metrics Details

  • Citations
    40
  • Captures
    36
  • Mentions
    2
    • Blog Mentions
      1
      • 1
    • References
      1
      • 1

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Viruses, Vol. 9, Pages 101: Cowpox virus: What’s in a Name?

Volume 9, Issue 5 ► ▼ Article Menu Article Versions Abstract Full-Text PDF [1791 KB] Full-Text HTML Full-Text XML Article Versions Notes Supplementary material Related

Article Description

Traditionally, virus taxonomy relied on phenotypic properties, however, a sequence-based virus taxonomy has become essential since the recent requirement of a species to exhibit monophyly. The species Cowpox virus has failed to meet this requirement, necessitating a reexamination of this species. Here, we report the genomic sequences of nine Cowpox viruses and, by combining them with the available data of 37 additional genomes, confirm polyphyly of Cowpox viruses and find statistical support based on genetic data for more than a dozen species. These results are discussed in light of the current International Committee on Taxonomy of Viruses species definition, as well as immediate and future implications for poxvirus taxonomic classification schemes. Data support the recognition of five monophyletic clades of Cowpox viruses as valid species.

Bibliographic Details

Mauldin, Matthew R; Antwerpen, Markus; Emerson, Ginny L; Li, Yu; Zoeller, Gudrun; Carroll, Darin S; Meyer, Hermann

MDPI AG

Medicine; Immunology and Microbiology

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