OB glue paste technique for establishing nude mouse human gastric cancer orthotopic transplantation models
World Journal of Gastroenterology, ISSN: 1007-9327, Vol: 14, Issue: 30, Page: 4800-4804
2008
- 16Citations
- 11Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations16
- Citation Indexes16
- 16
- CrossRef8
- Captures11
- Readers11
Article Description
Aim: To establish nude mouse human gastric cancer orthotopic transplantation models using OB glue paste technique. Methods: Using OB glue paste technique, orthtopic transplantation models were established by implanting SGC-7901 and MKN-45 human gastric cancer cell strains into the gastric wall of nude mice. Biological features, growth of the implanted tumors, the success rate of transplantation and the rate of auto-metastasis of the two models were observed. Results: The success rates of orthotopic transplantation of the two models were 94.20% and 96%. The rates of hepatic metastasis, pulmonary metastasis, peritoneal metastasis, lymphocytic metastasis and splenic metastasis were 42.13% and 94.20%, 48.43% and 57.97%, 30.83% and 36.96%, 67.30% and 84.06%, and 59.75% and 10.53%, respectively. The occurrence of ascites was 47.80% and 36.96%. Conclusion: OB glue paste technique is easy to follow. The biological behaviors of the nude mouse human gastric cancer orthotopic transplantation models established with this technique are similar to the natural processes of growth and metastasis of human gastric cancer, and, therefore, can be used as an ideal model for experimental research of proliferative metastasis of tumors. © 2008 The WJG Press. All rights reserved.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=55449088927&origin=inward; http://dx.doi.org/10.3748/wjg.14.4800; http://www.ncbi.nlm.nih.gov/pubmed/18720543; http://www.wjgnet.com/1007-9327/full/v14/i30/4800.htm; https://dx.doi.org/10.3748/wjg.14.4800; https://www.wjgnet.com/1007-9327/full/v14/i30/4800.htm
Baishideng Publishing Group Inc.
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