Effects of carbon dioxide and nitrogen on adhesive growth and expressions of E-cadherin and VEGF of human colon cancer cell CCL-228
World Journal of Gastroenterology, ISSN: 1007-9327, Vol: 9, Issue: 7, Page: 1594-1597
2003
- 12Citations
- 4Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations12
- Citation Indexes12
- 12
- CrossRef4
- Captures4
- Readers4
Article Description
Aim: To study the effects of carbon dioxide on the metastatic capability of cancer cells, and to compare them with that of nitrogen. Methods: The colon cancer cell CCL-228 was treated with 100 % carbon dioxide or nitrogen at different time points and then cultured under normal condition. Twelve hours after the treatment, the survival rates of suspension cells and the expressions of e-cadherin and VEGF were examined. Results: After 60 min of carbon dioxide and longer time of nitrogen treatment, the suspended cells increased and the expression of e-cadherin decreased while the expression of VEGF was enhanced significantly. And the effects of nitrogen were similar to, but weaker than, those of carbon dioxide. Conclusion: Carbon dioxide may improve the metastatic capability of cancer cells and its effects are significantly stronger than that of nitrogen. A sequential use of carbon dioxide and nitrogen in pneumoperitoneum may take the advantage of both gases.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0041563690&origin=inward; http://dx.doi.org/10.3748/wjg.v9.i7.1594; http://www.ncbi.nlm.nih.gov/pubmed/12854171; http://www.wjgnet.com/1007-9327/full/v9/i7/1594.htm; https://dx.doi.org/10.3748/wjg.v9.i7.1594; https://www.wjgnet.com/1007-9327/full/v9/i7/1594.htm
Baishideng Publishing Group Inc.
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