Serotonin transporter gene polymorphism and psychiatric disorders: Is there a link
Indian Journal of Psychiatry, ISSN: 0019-5545, Vol: 53, Issue: 4, Page: 289-299
2011
- 36Citations
- 111Captures
- 1Mentions
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations36
- Citation Indexes34
- 34
- CrossRef26
- Policy Citations2
- Policy Citation2
- Captures111
- Readers111
- 111
- Mentions1
- News Mentions1
- News1
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Review Description
Though still in infancy, the field of psychiatric genetics holds great potential to contribute to the development of new diagnostic and therapeutic options to treat these disorders. Among a large number of existing neurotransmitter systems, the serotonin system dysfunction has been implicated in many psychiatric disorders and therapeutic efficacy of many drugs is also thought to be based on modulation of serotonin. Serotonin transporter gene polymorphism is one of the most extensively studied polymorphisms in psychiatric behavioral genetics. In this article, we review the status of evidence for association between the serotonin gene polymorphism and some common mental disorders like affective disorders, post-traumatic stress disorder, obsessive-compulsive disorder, suicide, autism, and other anxiety and personality disorders. Going beyond traditional association studies, gene-environment interaction, currently gaining momentum, is also discussed in the review. While the existing information of psychiatric genetics is inadequate for putting into practice genetic testing in the diagnostic work-up of the psychiatric patient, if consistent in future research attempts, such results can be of great help to improve the clinical care of a vast majority of patients suffering from such disorders.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84856350819&origin=inward; http://dx.doi.org/10.4103/0019-5545.91901; http://www.ncbi.nlm.nih.gov/pubmed/22303036; https://journals.lww.com/10.4103/0019-5545.91901; https://dx.doi.org/10.4103/0019-5545.91901; https://www.indianjpsychiatry.org/article.asp?issn=0019-5545;year=2011;volume=53;issue=4;spage=289;epage=299;aulast=Margoob
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