Comparison of distinct approaches for screening the extended-spectrum beta-lactamase in Klebsiella pneumoniae and its biofilm formation on various catheter surfaces, antibiotic resistance profile before and after biofilm formation
Journal of Applied Biology and Biotechnology, ISSN: 2347-212X, Vol: 12, Issue: 1, Page: 165-171
2023
- 2Citations
- 2Captures
Metric Options: Counts1 Year3 YearSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Article Description
The aim of the study was to determine the antibiotic resistance profiles of Klebsiella pneumoniae, their extended-spectrum beta-lactamase (ESBL) production and biofilm formation on two different catheter surfaces along with its antibiotic resistance profile. Nearly, 47 K. pneumoniae strains were procured from K.A.P. Viswanatham Government Medical College, Trichy, Tamil Nadu, India. The tested strains exhibited 29 distinct antibiotic resistance patterns. From 47 K. pneumoniae, 93.6% (n = 44/47) were screened positive for ESBL by phenotypic confirmatory disk diffusion test (PCDDT). Furthermore, all the isolates were subjected to double disk synergy test (DDST), only 82.9% (n = 39/47) isolates were found to be positive. However, in modified double disk synergy test (MDDST) 97.8% (n = 46/47) isolates were positive, whereas in direct modified three dimensional test (DMTDT) 36.1% (n = 17/47) isolates were found to be positive and indirect modified three dimensional test (IMTDT) it was 87.2% (n = 41/47). The quantification of K. pneumoniae biofilm formation over two distinct catheter surfaces revealed that polyvinyl chloride (PVC) based catheter found to be adhered high number of cells than in silicon elastomer bonded catheter surface. Similarly, the biofilm formation of the strains grown with glucose in trypticase soya broth (TSBG) enhanced adherence ability. Moreover, enhanced antibiotic resistance of K. pneumoniae was found in the strains following the biofilm development. It is concluded that the existence of ESBL-positive isolates and glucose or other sugar substrates facilitates biofilm development, resulting in high resistance to several antibiotics. This circumstance is detrimental to human health.
Bibliographic Details
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know