Need of multimodal SPECT/MRI for tracking ofin-labeled human mesenchymal stem cells in neuroblastoma tumor-bearing mice
IFMBE Proceedings, ISSN: 1680-0737, Vol: 41, Page: 392-394
2014
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Conference Paper Description
Tumor-homing is a complex, multistep process used by many cells, like mesenchymal stem cells (MSCs), to travel from a distant location to a tumor. The purpose of this study is to investigate the applicability of 111In-oxine for tracking human MSCs in vivo with single photon emission computed tomography (SPECT) and magnetic resonance imaging (MRI). 111In labeled hMSCs (106 cells) were infused intraperitoneally in neuroblastoma tumor-bearing mice, and SPECT/MRI images were performed 24 and 48 hour afterwards. High initial hMSC localization occurred in the abdomen cavity and 48 hour later hMSC-injected animals showed tumor uptake. MRI information was essential to properly define Regions of Interest on the images. Tracking 111In labeled hMSC combining SPECT and MRI is feasible and may be transferable to human studies. © Springer International Publishing Sw itzerland 2014.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84891319367&origin=inward; http://dx.doi.org/10.1007/978-3-319-00846-2_97; https://link.springer.com/10.1007/978-3-319-00846-2_97; https://dx.doi.org/10.1007/978-3-319-00846-2_97; https://link.springer.com/chapter/10.1007/978-3-319-00846-2_97
Springer Science and Business Media LLC
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